About SPD503 (guanfacine HCl extended release): SPD503 is at
present under costing with FDA for the treatment of ADHD in
children aged 6 to 17 years. SPD503 is a once-daily formulation
of the selective alpha-2A-adrenoceptor agonist guanfacine and was
studied to determine if it provide control of ADHD symptoms
throughout the daytime in children aged 6 to 17 years. The most
commonly reported treatment-emergent adverse events were
headache, somnolence, fatigue, upper abdominal pain and sedation.
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